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Takanobu Yamazaki Selected Research

Overactive Urinary Bladder (Overactive Bladder)

7/2022Vibegron inhibits enhanced spontaneous contractions induced by anoxia/reoxygenation in isolated whole bladder from rats.
12/2019Effects of the combination of vibegron and imidafenacin on bladder function in urethane-anesthetized rats.
11/2016Imidafenacin exerts the antidiuretic effect by enhancing vasopressin-related responses in orally water-loaded rats.
12/2013Imidafenacin has no influence on learning in nucleus basalis of Meynert-lesioned rats.
9/2011In vivo bladder selectivity of imidafenacin, a novel antimuscarinic agent, assessed by using an effectiveness index for bladder capacity in rats.
1/2007Pharmacological effects of imidafenacin (KRP-197/ONO-8025), a new bladder selective anti-cholinergic agent, in rats. Comparison of effects on urinary bladder capacity and contraction, salivary secretion and performance in the Morris water maze task.

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Takanobu Yamazaki Research Topics

Disease

6Overactive Urinary Bladder (Overactive Bladder)
07/2022 - 01/2007
2Cognitive Dysfunction
12/2013 - 01/2007
1Hypoxia (Hypoxemia)
07/2022
1Ischemia
07/2022
1Urinary Bladder Neck Obstruction (Bladder Neck Obstruction)
07/2020
1Alzheimer Disease (Alzheimer's Disease)
12/2013
1Bradycardia
09/2011
1Dizziness (Lightheadedness)
01/2011
1Stroke (Strokes)
01/2011

Drug/Important Bio-Agent (IBA)

4imidafenacinIBA
07/2020 - 01/2007
4Muscarinic AntagonistsIBA
12/2019 - 09/2011
2N- (4- ((5- (hydroxy(phenyl)methyl)pyrrolidin- 2- yl)methyl)phenyl)- 4- oxo- 4,6,7,8- tetrahydropyrrolo(1,2- a)pyrimidine- 6- carboxamideIBA
07/2022 - 07/2020
1Potassium Channels (Potassium Channel)IBA
07/2022
1Krebs-Ringer solutionIBA
07/2022
1silodosinFDA Link
07/2020
1Antidiuretic AgentsIBA
11/2016
1Carbachol (Carbastat)FDA Link
09/2011
1ibudilastIBA
01/2011
1Phosphoric Diester Hydrolases (Phosphodiesterases)IBA
01/2011
1Vasodilator Agents (Vasodilators)IBA
01/2011
1Cholinergic Antagonists (Anticholinergics)IBA
01/2007
1Cholinergic Agents (Cholinergics)IBA
01/2007
1Acetylcholine (Acetylcholine Chloride)FDA Link
01/2007